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Research projects

img oxidative 2Medicinal Plant Research

  • Rooibos and Honeybush: Recent advances in chemistry, biological activity and pharmacognosy.
  • Modulation of oxidative stress biomarkers by rooibos in adults at risk of developing heart disease.
  • Rooibos: effect on iron status in South African adults at risk for coronary heart disease.
  • The role of rooibos (Aspalathus linearis), green tea (Camellia sinensis) and commercially available rooibos and green tea antioxidant supplements on rat testicular and epididymal function.
  • Antioxidant status of South African beverages and its role on the chemical parameters in human blood.
  • Modulation of ultraviolet light-induced skin carcinogenesis by extracts of rooibos and honeybush using a mouse model: elucidating possible protective mechanisms.
  • Development and evaluation of a Food frequency questionnaire to assess daily total flavonoid intake using a rooibos intervention study model.
  • Effect of fluid substitutions on the total antioxidant capacity of breads: comparing the indigenous herbal teas rooibos and honeybush with black tea.
  • Effect on the total antioxidant capacity of substituting water with rooibos herbal teas in popular soup recipes.
  • Investigations on the antifungal and cancer modulating properties of extracts from selected species of Tulbaghia.
  • Modulation of oxidative stress by rooibos (Aspalathus linearis) herbal tea, Chinese green tea (Camellia sinensis) and commercial tea supplements using a rodent model.
  • Validation of two bio-analytical assays for the measurement of hydrophilic antioxidant capacity in several food and beverage commodities in accordance with ISO 17025 regulatory guidelines.
  • Improved modulation of the endogenous antioxidant system and inflammatory responses in male Wistar rats by rooibos (Aspalathus linearis) and red palm oil (Elaeis guineensis).
  • Development of analytical assays to measure oxidative stress in the stratum corneum using skin tape strips.
  • Rooibos (Aspalathus linearis) offers cardiac protection against ischaemia/reperfusion in the isolated perfused rat heart.
  • Modulation of postprandial oxidative stress by rooibos (Aspalathus linearis) in normal lipemic individuals.
  • Comparative antioxidant-capacity and -content of leaves, bulbs, roots, flowers and fruit of Gethyllis multifolia L. Bolus and G. villosa Thunb. species.
  • Modulation of LPS-Induced CD4+ T-Cell Activation and apoptosis by antioxidants in untreated asymptomatic HIV infected participants: an in vitro study.
  • Heavy metal contamination and antioxidant responses of Mytilus galloprovincialis along the west coast of the Cape Peninsula, South Africa.
  • Health claims on the benefits of moderate alcohol consumption in relation to genetic profiles.
  • Salinity induced changes in oxidative stress and antioxidant status as affected by applications of silicon in lettuce (Lactuca sativa).
  • Protective effects of rooibos (Aspalathus linearis) and/or red palm oil (Elaeis guineensis) supplementation on tert-butyl hydroperoxide-induced oxidative hepatotoxicity in Wistar rats.
  • Assessment of the impact of hereditary factors on biochemical parameters of cardiovascular risk in relation to moderate alcohol consumption.
  • Rooibos influences glucocorticoid levels and steroid ratios in vivo and in vitro: A natural approach in the management of stress and metabolic disorders?